Zinepra 10 Tablet SR

Zinepra 10 Tablet SR
Propranolol (40mg) + Flunarizine (10mg)
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About This Medicine
Product description & overview
Zinepra 10 Tablet SR is a sustained-release formulation combining Propranolol 40 mg and Flunarizine 10 mg, designed for the management of migraine prophylaxis and related vascular disorders. Propranolol, a non-selective beta-adrenergic blocker, exerts its therapeutic effect by reducing cardiac output and inhibiting beta-receptors in the central nervous system, thereby decreasing the frequency and severity of migraine attacks. Flunarizine, a calcium channel blocker with antihistaminic properties, contributes to migraine prevention by inhibiting calcium influx into vascular smooth muscle cells, stabilizing neuronal excitability, and reducing cerebral vasospasm. The sustained-release mechanism ensures a gradual and consistent release of active ingredients, enhancing patient compliance and minimizing peak-related side effects. Zinepra 10 Tablet SR is indicated for patients requiring long-term management of migraines, particularly those with comorbid hypertension or anxiety disorders where beta-blockade is beneficial. It should be used under medical supervision, with caution advised in patients with asthma, bradycardia, or heart block. Common adverse effects may include fatigue, dizziness, gastrointestinal disturbances, and mild hypotension. Regular monitoring of cardiovascular status is recommended during therapy. This combination offers a synergistic approach to migraine prophylaxis, improving quality of life for patients with recurrent migraine episodes.
Active composition
Propranolol 40 mg
+1 more active ingredient
About Propranolol
Propranolol is a non-selective beta-adrenergic antagonist used to manage various cardiovascular conditions, including hypertension, angina, and arrhythmias. It is also effective in preventing migraines and alleviating symptoms of anxiety. By blocking beta receptors, Propranolol reduces heart rate and myocardial contractility, leading to decreased cardiac workload. In summary, Propranolol is a versatile medication essential for managing heart-related conditions and anxiety.
How It Works
Propranolol blocks beta-1 and beta-2 adrenergic receptors, resulting in decreased heart rate, myocardial contractility, and overall cardiac output.
All Active Ingredients
Flunarizine
Flunarizine acts as a calcium channel blocker, preventing vasodilation and reducing the frequency of migraine attacks.
Dosage & How to Use
Dosage information not available. Please consult your doctor or pharmacist.
Safety Advice
Important precautions
Safety information not available for this product. Please consult your doctor or pharmacist.
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