Zinase-DP Tablet is a combination analgesic and anti-inflammatory medication containing Diclofenac 50 mg, Paracetamol 325 mg, and Serratiopeptidase 10 mg. Diclofenac, a nonsteroidal anti-inflammatory drug (NSAID), exerts potent anti-inflammatory, analgesic, and antipyretic effects by inhibiting cyclooxygenase enzymes, thereby reducing prostaglandin synthesis. Paracetamol provides effective analgesia and antipyresis through central inhibition of prostaglandin synthesis, complementing Diclofenac’s peripheral action. Serratiopeptidase, a proteolytic enzyme, facilitates the breakdown of inflammatory mediators and promotes the resolution of edema and inflammation, enhancing tissue repair and reducing pain and swelling. This combination is indicated for the management of acute and chronic musculoskeletal pain, postoperative inflammation, arthritis, and other inflammatory conditions where both pain relief and reduction of inflammation are desired. Zinase-DP Tablet should be used under medical supervision, with caution in patients with gastrointestinal ulcers, hepatic or renal impairment, and hypersensitivity to any component. Common adverse effects may include gastrointestinal discomfort, nausea, and allergic reactions. The dosage and duration of therapy should be individualized based on clinical response and tolerability. This formulation offers a synergistic approach to pain and inflammation management, improving patient compliance and therapeutic outcomes.