Zerodol TH Max 8 Tablet is a combination analgesic and anti-inflammatory medication formulated with Thiocolchicoside (8 mg), Aceclofenac (100 mg), and Paracetamol (325 mg). Thiocolchicoside is a muscle relaxant that acts by selectively blocking glycine receptors, thereby alleviating muscle spasms and associated pain. Aceclofenac, a non-steroidal anti-inflammatory drug (NSAID), inhibits cyclooxygenase enzymes (COX-1 and COX-2), reducing the synthesis of prostaglandins responsible for inflammation, pain, and swelling. Paracetamol provides analgesic and antipyretic effects by inhibiting central prostaglandin synthesis, complementing the anti-inflammatory action of Aceclofenac. This combination is indicated for the management of acute musculoskeletal conditions such as muscle spasms, strains, sprains, and inflammatory disorders including osteoarthritis and rheumatoid arthritis. Zerodol TH Max 8 Tablet offers effective relief from pain, inflammation, and muscle stiffness, improving patient mobility and quality of life. It should be used under medical supervision, with caution advised in patients with hepatic, renal, or gastrointestinal impairment. Common side effects may include gastrointestinal discomfort, dizziness, or allergic reactions. Contraindications include hypersensitivity to any component, active peptic ulcer, and severe hepatic or renal dysfunction. Proper dosing and duration should be adhered to, minimizing risk of adverse effects.