Zeldinac S 50mg/10mg Tablet is a combination medication containing Diclofenac 50mg and Serratiopeptidase 10mg, indicated for the management of inflammatory conditions and associated pain. Diclofenac, a nonsteroidal anti-inflammatory drug (NSAID), exerts its therapeutic effect by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), thereby reducing the synthesis of prostaglandins responsible for inflammation, pain, and fever. Serratiopeptidase is a proteolytic enzyme that facilitates the breakdown of inflammatory mediators and promotes the resolution of edema and swelling by enhancing fibrinolytic activity. The synergistic action of these agents provides effective relief in conditions such as osteoarthritis, rheumatoid arthritis, musculoskeletal injuries, postoperative inflammation, and soft tissue disorders. Zeldinac S is typically administered orally, with dosage and duration tailored according to the severity of the condition and patient response. Caution is advised in patients with a history of gastrointestinal ulcers, bleeding disorders, or hypersensitivity to NSAIDs or serratiopeptidase. Common adverse effects may include gastrointestinal discomfort, nausea, and allergic reactions. It is recommended to use this medication under medical supervision, with periodic monitoring for potential side effects, especially during prolonged therapy.