Zeblong 16mg Tablet contains Azelnidipine, a long-acting calcium channel blocker used primarily for the management of hypertension. Azelnidipine selectively inhibits the influx of calcium ions through L-type calcium channels in vascular smooth muscle, leading to vasodilation and a consequent reduction in peripheral vascular resistance. This mechanism helps lower elevated blood pressure, thereby reducing the risk of cardiovascular events such as stroke and myocardial infarction. Zeblong is typically administered once daily due to its prolonged duration of action, ensuring sustained blood pressure control over 24 hours. The tablet is indicated for patients with essential hypertension, either as monotherapy or in combination with other antihypertensive agents when monotherapy is insufficient. Azelnidipine is generally well tolerated; common adverse effects may include headache, dizziness, flushing, and peripheral edema. Caution is advised in patients with severe hypotension, aortic stenosis, or heart failure. Regular monitoring of blood pressure and clinical status is recommended to assess therapeutic response and detect potential adverse reactions. Zeblong 16mg Tablet should be used under medical supervision, with dosage adjustments based on individual patient response and tolerability.