Zalex F 5 Tablet contains a combination of Fluoxetine 20 mg and Olanzapine 5 mg, formulated for the treatment of major depressive disorder with psychotic features, treatment-resistant depression, and certain bipolar disorders. Fluoxetine, a selective serotonin reuptake inhibitor (SSRI), functions by increasing serotonin levels in the brain, thereby improving mood, emotional balance, and anxiety symptoms. Olanzapine, an atypical antipsychotic, modulates the activity of dopamine and serotonin receptors, helping to manage psychotic symptoms such as hallucinations, delusions, and mood swings. The synergistic effect of these two agents provides enhanced therapeutic benefits in patients who do not respond adequately to monotherapy. Zalex F 5 Tablet is typically prescribed under strict medical supervision, with dosage adjustments based on patient response and tolerability. Common side effects may include weight gain, sedation, dry mouth, dizziness, and gastrointestinal disturbances. Caution is advised in patients with a history of cardiovascular disease, diabetes, or seizure disorders. Regular monitoring of metabolic parameters and mental status is recommended during treatment. Zalex F 5 Tablet should not be discontinued abruptly to avoid withdrawal symptoms. It is contraindicated in patients with hypersensitivity to its components and should be used cautiously during pregnancy and lactation.