Zacuvas 10 Tablet contains Rosuvastatin 10mg, a potent lipid-lowering agent belonging to the statin class of medications. It is primarily indicated for the treatment of hypercholesterolemia and mixed dyslipidemia to reduce elevated total cholesterol, low-density lipoprotein cholesterol (LDL-C), apolipoprotein B, and triglycerides, while increasing high-density lipoprotein cholesterol (HDL-C). Rosuvastatin acts by selectively inhibiting HMG-CoA reductase, the rate-limiting enzyme in cholesterol biosynthesis, thereby decreasing cholesterol production in the liver and enhancing LDL receptor expression to promote clearance of LDL from the bloodstream. Zacuvas 10 is utilized both as monotherapy and as adjunctive therapy to diet and lifestyle modifications in patients at risk for atherosclerotic cardiovascular disease (ASCVD), including those with primary hyperlipidemia, mixed dyslipidemia, and familial hypercholesterolemia. The recommended dosage should be individualized based on patient response and risk profile, with regular monitoring of lipid levels and liver function tests. Common adverse effects may include headache, myalgia, and gastrointestinal disturbances; rare but serious risks include myopathy and hepatotoxicity. Zacuvas 10 should be used cautiously in patients with pre-existing liver disease or renal impairment and is contraindicated during pregnancy and lactation.