Xircox TH4 Tablet is a combination medication containing Etoricoxib 60mg and Thiocolchicoside 4mg, formulated for the management of musculoskeletal pain and inflammation. Etoricoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, provides effective analgesic and anti-inflammatory effects by reducing the synthesis of prostaglandins involved in pain and inflammation pathways, thereby minimizing gastrointestinal side effects commonly associated with non-selective NSAIDs. Thiocolchicoside, a muscle relaxant with antispasmodic properties, acts on GABAergic and glycinergic receptors to alleviate muscle stiffness and spasms, improving mobility and comfort. Xircox TH4 is indicated for the treatment of acute musculoskeletal conditions such as low back pain, osteoarthritis, and muscle spasms associated with inflammatory disorders. The combination offers synergistic benefits by concurrently addressing inflammation, pain, and muscle spasm, facilitating faster relief and functional recovery. It is recommended to be used under medical supervision, with dosage adjustments based on patient response and tolerability. Contraindications include hypersensitivity to either component, active gastrointestinal ulcers, severe hepatic or renal impairment, and cardiovascular risk factors. Patients should be monitored for adverse effects such as gastrointestinal discomfort, dizziness, or allergic reactions. Xircox TH4 Tablet should be used cautiously in patients with pre-existing cardiovascular or renal conditions.