Xaldinac Tablet is a combination medication containing Diclofenac 50 mg and Metaxalone 400 mg, formulated for the management of musculoskeletal pain and inflammation. Diclofenac, a nonsteroidal anti-inflammatory drug (NSAID), exerts its effect by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), thereby reducing the synthesis of prostaglandins responsible for pain and inflammation. Metaxalone is a centrally acting skeletal muscle relaxant that alleviates muscle spasms by depressing nerve impulses in the central nervous system. The synergistic action of these two agents provides effective relief from acute musculoskeletal conditions such as strains, sprains, and other soft tissue injuries. Xaldinac is indicated for short-term use in patients requiring both anti-inflammatory and muscle relaxant therapy. It should be used with caution in individuals with a history of gastrointestinal disorders, cardiovascular disease, or hepatic impairment. Common adverse effects may include gastrointestinal discomfort, dizziness, and drowsiness. Patients are advised to avoid alcohol and operate machinery cautiously while on this medication. Xaldinac Tablet should be administered as prescribed by a healthcare professional, and it is important to adhere to recommended dosages to minimize the risk of adverse reactions.