Withnerv-NP Tablet SR is a sustained-release formulation combining Pregabalin 75 mg, Nortriptyline 10 mg, and Methylcobalamin 1500 mcg, designed for the management of neuropathic pain and associated conditions. Pregabalin, a gamma-aminobutyric acid (GABA) analogue, modulates calcium channel function to reduce neurotransmitter release, thereby alleviating neuropathic pain and improving nerve function. Nortriptyline, a tricyclic antidepressant, enhances noradrenergic and serotonergic neurotransmission, contributing to analgesic effects and mood stabilization in chronic pain states. Methylcobalamin, an active form of vitamin B12, supports nerve regeneration and repair by promoting myelin sheath synthesis and neuronal metabolism. The combination offers a multimodal approach to neuropathic pain management, addressing pain relief, nerve healing, and psychological well-being. Withnerv-NP Tablet SR is indicated for peripheral neuropathies, diabetic neuropathy, postherpetic neuralgia, and other neuropathic pain syndromes. The sustained-release formulation ensures prolonged therapeutic levels, improving patient compliance and minimizing side effects. It should be used under medical supervision, with dosage adjustments based on clinical response and tolerability. Common adverse effects may include dizziness, dry mouth, sedation, and gastrointestinal disturbances. Caution is advised in patients with renal impairment, cardiovascular disease, or a history of seizures.