Oxivik-Tryo Tablet is a combination medication containing Pregabalin (75 mg), Nortriptyline (10 mg), and Methylcobalamin (1500 mcg), formulated for the management of neuropathic pain and associated conditions. Pregabalin, a gamma-aminobutyric acid (GABA) analogue, modulates calcium channel function to reduce neuronal excitability and alleviate neuropathic pain. Nortriptyline, a tricyclic antidepressant, exerts analgesic effects by inhibiting the reuptake of norepinephrine and serotonin, thereby enhancing descending inhibitory pain pathways. Methylcobalamin, an active form of vitamin B12, supports nerve regeneration and repair by promoting myelin sheath synthesis and neuronal metabolism. The synergistic action of these components provides effective relief from chronic neuropathic pain, diabetic neuropathy, postherpetic neuralgia, and other peripheral neuropathies. Oxivik-Tryo is indicated for patients requiring multimodal therapy to improve pain control and nerve function. It should be used under medical supervision with caution in patients with renal impairment, cardiovascular disorders, or a history of seizures. Common adverse effects may include dizziness, drowsiness, dry mouth, and gastrointestinal disturbances. Dose adjustments may be necessary based on clinical response and tolerability. This combination tablet offers a comprehensive approach to neuropathic pain management by addressing both symptomatic relief and underlying nerve health.