Orthosenz Ointment

Orthosenz Ointment
Capsaicin (0.025% w/w) + Diclofenac (4% w/w) + Gabapentin (8% w/w) + Methyl Salicylate (5% w/w)
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About This Medicine
Product description & overview
Orthosenz Ointment is a topical formulation combining Capsaicin (0.025% w/w), Diclofenac (4% w/w), Gabapentin (8% w/w), and Methyl Salicylate (5% w/w) designed for the management of musculoskeletal pain and neuropathic discomfort. Capsaicin acts by depleting substance P, thereby reducing pain signal transmission. Diclofenac, a nonsteroidal anti-inflammatory drug (NSAID), provides anti-inflammatory and analgesic effects by inhibiting cyclooxygenase enzymes, reducing prostaglandin synthesis. Gabapentin, an anticonvulsant with analgesic properties, modulates calcium channels to alleviate neuropathic pain. Methyl Salicylate serves as a counterirritant, producing a warming sensation that helps distract from underlying pain. The combination of these active ingredients offers a multimodal approach to pain relief, targeting inflammation, neuropathic pain, and providing symptomatic comfort. Orthosenz Ointment is indicated for conditions such as osteoarthritis, rheumatoid arthritis, neuropathic pain syndromes, and soft tissue injuries. It should be applied topically to the affected area, avoiding broken or irritated skin. Use with caution in patients with hypersensitivity to salicylates or NSAIDs. Common adverse effects may include local skin irritation or burning sensation. Consult a healthcare professional before use, especially in pregnant or lactating women and patients with pre-existing medical conditions.
Active composition
Capsaicin
+3 more active ingredients
All Active Ingredients
Diclofenac
Diclofenac inhibits COX-1 and COX-2 enzymes, leading to decreased synthesis of prostaglandins, which mediate pain and inflammation.
Gabapentin
Gabapentin binds to the alpha-2-delta subunit of voltage-gated calcium channels, inhibiting excitatory neurotransmitter release and reducing neuronal excitability.
Dosage & How to Use
Dosage information not available. Please consult your doctor or pharmacist.
Safety Advice
Important precautions
Safety information not available for this product. Please consult your doctor or pharmacist.
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