Olanex Plus 10 Tablet is a combination pharmaceutical formulation containing Fluoxetine 20 mg and Olanzapine 10 mg, primarily indicated for the treatment of major depressive disorder with psychotic features, treatment-resistant depression, and certain bipolar disorders. Fluoxetine, a selective serotonin reuptake inhibitor (SSRI), functions by increasing serotonin levels in the brain, thereby improving mood and alleviating depressive symptoms. Olanzapine, an atypical antipsychotic, acts by modulating dopamine and serotonin receptors, helping to manage psychotic symptoms such as hallucinations, delusions, and mood stabilization. The synergistic effect of these two active ingredients provides enhanced therapeutic benefits in patients exhibiting both depressive and psychotic symptoms. Olanex Plus 10 is typically administered once daily, with dosage adjustments based on clinical response and tolerability. Common adverse effects may include weight gain, sedation, dry mouth, gastrointestinal disturbances, and extrapyramidal symptoms. Caution is advised in patients with a history of cardiovascular disease, diabetes, or seizure disorders. Regular monitoring of metabolic parameters and mental status is recommended during treatment. Olanex Plus 10 should be used under strict medical supervision, with gradual dose titration and careful assessment of risk-benefit ratio to optimize therapeutic outcomes and minimize potential side effects.