Obimet GX Forte 1mg Tablet PR is a combination oral antidiabetic medication containing Glimepiride 1mg and Metformin 1000mg, indicated for the management of type 2 diabetes mellitus. Glimepiride, a sulfonylurea class agent, stimulates pancreatic beta cells to increase insulin secretion, thereby reducing blood glucose levels. Metformin, a biguanide, primarily acts by decreasing hepatic glucose production and improving peripheral insulin sensitivity, enhancing glucose uptake in muscle tissues. The combination of these two agents offers complementary mechanisms of action, providing effective glycemic control in patients inadequately managed by diet and exercise alone. Obimet GX Forte is typically prescribed as part of a comprehensive diabetes management plan, including diet modification and regular physical activity. It is important to monitor blood glucose levels regularly to adjust dosage and avoid hypoglycemia, a potential adverse effect primarily associated with Glimepiride. Metformin's common side effects include gastrointestinal disturbances such as nausea and diarrhea, which often subside with continued use. This medication is contraindicated in patients with renal impairment, hepatic dysfunction, or conditions predisposing to hypoxia. Healthcare providers should evaluate patient history and renal function prior to initiation and during therapy to ensure safe and effective treatment outcomes.