Nvm Dolo Tablet SR is a sustained-release formulation combining Methylcobalamin 1500 mcg and Pregabalin 75 mg, designed for the management of neuropathic pain and related neurological disorders. Methylcobalamin, an active form of vitamin B12, plays a crucial role in nerve regeneration and repair by promoting myelin sheath synthesis and enhancing neuronal function. Pregabalin, an anticonvulsant and analgesic agent, modulates calcium channel activity in the central nervous system, thereby reducing the release of excitatory neurotransmitters and alleviating neuropathic pain symptoms such as burning, shooting, or stabbing sensations. This combination is particularly effective in conditions like diabetic neuropathy, postherpetic neuralgia, and peripheral neuropathies. The sustained-release formulation ensures a gradual and prolonged release of active ingredients, improving patient compliance by reducing dosing frequency and maintaining stable plasma drug levels. Nvm Dolo Tablet SR should be used under medical supervision, with dosage adjustments based on clinical response and tolerability. Common adverse effects may include dizziness, somnolence, and gastrointestinal disturbances. Caution is advised in patients with renal impairment, and it is contraindicated in individuals with known hypersensitivity to either component. This combination therapy offers a comprehensive approach to neuropathic pain management by addressing both symptomatic relief and nerve repair mechanisms.