Nurorise P Tablet SR is a sustained-release formulation combining Methylcobalamin 1500 mcg and Pregabalin 75 mg, designed for the management of neuropathic pain and associated neurological conditions. Methylcobalamin, an active form of vitamin B12, plays a crucial role in nerve regeneration and repair, supporting the maintenance of healthy nerve function and aiding in the treatment of peripheral neuropathies. Pregabalin, a gamma-aminobutyric acid (GABA) analogue, exerts its therapeutic effect by modulating calcium channels in the central nervous system, thereby reducing neuronal excitability and alleviating neuropathic pain symptoms such as burning, shooting pain, and allodynia. The sustained-release mechanism ensures a gradual and prolonged release of active ingredients, enhancing patient compliance by reducing dosing frequency and maintaining stable plasma drug levels. Nurorise P Tablet SR is indicated for conditions including diabetic neuropathy, postherpetic neuralgia, fibromyalgia, and other neuropathic pain syndromes. It should be used under medical supervision, with careful consideration of patient history, renal function, and potential drug interactions. Common side effects may include dizziness, somnolence, and gastrointestinal disturbances. Dose adjustments may be necessary in renal impairment. Nurorise P Tablet SR offers a synergistic approach to neuropathic pain management by combining neurotrophic support with effective analgesia.