Nuromark-PNT Tablet SR is a sustained-release formulation combining Pregabalin 75 mg, Nortriptyline 10 mg, and Methylcobalamin 1500 mcg, designed for the management of neuropathic pain and associated conditions. Pregabalin, an anticonvulsant and analgesic agent, modulates calcium channel function to reduce neurotransmitter release, thereby alleviating neuropathic pain symptoms. Nortriptyline, a tricyclic antidepressant, enhances noradrenergic and serotonergic neurotransmission, contributing to pain relief and mood stabilization. Methylcobalamin, an active form of vitamin B12, supports nerve regeneration and repair, promoting neural health and functional recovery. The sustained-release mechanism ensures a gradual and prolonged therapeutic effect, improving patient compliance and minimizing peak-related side effects. Nuromark-PNT is indicated for diabetic neuropathy, postherpetic neuralgia, peripheral neuropathies, and other chronic neuropathic pain syndromes. It should be used under medical supervision, with dosage adjustments based on clinical response and tolerability. Common adverse effects may include dizziness, somnolence, dry mouth, and gastrointestinal disturbances. Caution is advised in patients with renal impairment, cardiac conditions, or a history of seizures. Nuromark-PNT Tablet SR offers a multimodal approach to neuropathic pain management, combining analgesic, antidepressant, and neurotrophic effects in a single, convenient dosage form.