Nureeto 90 Tablet contains Etoricoxib 90 mg, a selective cyclooxygenase-2 (COX-2) inhibitor used primarily for the management of pain and inflammation associated with various musculoskeletal and inflammatory conditions. Etoricoxib acts by selectively inhibiting the COX-2 enzyme, thereby reducing the synthesis of prostaglandins responsible for pain and inflammation while sparing COX-1, which helps maintain gastrointestinal mucosal integrity. This selective mechanism offers effective analgesic and anti-inflammatory effects with a potentially lower risk of gastrointestinal adverse effects compared to non-selective nonsteroidal anti-inflammatory drugs (NSAIDs). Nureeto 90 is indicated for symptomatic relief in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and acute gouty arthritis. It is also used for managing chronic musculoskeletal pain and postoperative dental pain. The recommended dosage should be individualized based on the patient’s clinical condition and response, with caution advised in patients with cardiovascular risk factors, renal or hepatic impairment. Common side effects may include headache, dizziness, hypertension, and gastrointestinal discomfort. Nureeto 90 should be used under medical supervision, particularly in patients with a history of cardiovascular disease or gastrointestinal ulcers. Regular monitoring is advised during prolonged therapy to ensure safety and efficacy.