Nureeto 60 Tablet contains Etoricoxib 60 mg, a selective cyclooxygenase-2 (COX-2) inhibitor used primarily for the management of pain and inflammation associated with various musculoskeletal and joint disorders. Etoricoxib acts by selectively inhibiting the COX-2 enzyme, thereby reducing the synthesis of prostaglandins responsible for inflammation, pain, and swelling, while sparing COX-1 enzyme activity, which helps maintain gastrointestinal mucosal integrity. Nureeto 60 is indicated for the treatment of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and acute gouty arthritis. It is also effective in managing chronic musculoskeletal pain and postoperative pain. The recommended dosage should be individualized based on the patient's condition and response, with a typical dose of 60 mg once daily. Caution is advised in patients with a history of cardiovascular disease, hypertension, renal impairment, or gastrointestinal disorders. Nureeto 60 should be used at the lowest effective dose for the shortest duration necessary to minimize potential adverse effects. Common side effects may include headache, dizziness, gastrointestinal discomfort, and elevated blood pressure. It is contraindicated in patients with hypersensitivity to Etoricoxib or other NSAIDs, active peptic ulceration, and severe hepatic or renal impairment. Regular monitoring is recommended during prolonged therapy.