Nufulvin 250mg Tablet contains Griseofulvin 250mg, an antifungal agent primarily used for the treatment of dermatophytic infections of the skin, hair, and nails. Griseofulvin acts by inhibiting fungal cell mitosis through disruption of microtubule function, thereby preventing fungal cell division and growth. This medication is indicated for superficial mycoses caused by dermatophytes such as Trichophyton, Microsporum, and Epidermophyton species, including tinea corporis, tinea capitis, tinea pedis, and onychomycosis. Nufulvin is administered orally and is absorbed better when taken with fatty meals, enhancing its bioavailability. The typical dosage varies depending on the severity and type of infection, with treatment duration often extending from several weeks to months to ensure complete eradication of the fungus and prevent relapse. Common adverse effects may include headache, gastrointestinal disturbances such as nausea and diarrhea, and hypersensitivity reactions. Caution is advised in patients with hepatic impairment or porphyria. Griseofulvin is contraindicated in pregnancy due to potential teratogenic effects. Patients should be advised to avoid alcohol consumption during therapy as it may induce a disulfiram-like reaction. Regular monitoring and adherence to prescribed duration are essential for optimal therapeutic outcomes.