Nufocal Soft Gel Capsule is a combination pharmaceutical formulation containing Calcitriol (0.25 mcg), Calcium citrate (500 mg), and Zinc Sulphate Monohydrate (7.5 mg), designed to support bone health and mineral metabolism. Calcitriol, the active form of vitamin D3, plays a crucial role in calcium homeostasis by enhancing intestinal absorption of calcium and phosphate, thereby promoting bone mineralization. Calcium citrate serves as an essential mineral supplement, providing bioavailable calcium necessary for maintaining normal bone density and preventing osteoporosis. Zinc Sulphate Monohydrate contributes to enzymatic functions and supports immune health, while also playing a role in bone tissue repair and regeneration. Nufocal is indicated for the management of conditions associated with calcium and vitamin D deficiency such as osteoporosis, hypocalcemia, osteomalacia, and certain metabolic bone disorders. It is particularly beneficial in patients with impaired calcium absorption or increased calcium requirements. The soft gel capsule formulation facilitates ease of administration and improved bioavailability. Caution is advised in patients with hypercalcemia, hypervitaminosis D, or renal impairment. Regular monitoring of serum calcium and renal function is recommended during prolonged therapy to avoid potential adverse effects such as hypercalcemia or nephrolithiasis. Nufocal should be used under medical supervision to ensure optimal therapeutic outcomes.