Nexavar 200mg Tablets contain Sorafenib, an orally active multi-kinase inhibitor. It is primarily indicated for the treatment of advanced renal cell carcinoma and hepatocellular carcinoma. Nexavar works by blocking multiple kinases involved in angiogenesis, cell proliferation, and apoptosis. The recommended dose is 400mg orally, twice daily, with meals. It should be taken continuously until disease progression or unacceptable toxicity occurs. Common adverse reactions include hand-foot skin reaction, diarrhea, fatigue, and hypertension. Prothrombin time, blood pressure, and liver function should be regularly monitored during treatment. Use with caution in patients with significant cardiovascular disease, active bleeding, or severe hepatic impairment. Pregnant women should avoid handling crushed or broken tablets due to potential fetal toxicity.