Metlin M 75 Tablet SR is a sustained-release formulation combining Methylcobalamin 1500 mcg and Pregabalin 75 mg, designed for the management of neuropathic pain and related neurological disorders. Methylcobalamin, an active form of vitamin B12, plays a crucial role in nerve regeneration and repair by promoting myelin sheath synthesis and enhancing neuronal function. Pregabalin, an anticonvulsant and analgesic agent, modulates calcium channel activity in the central nervous system, thereby reducing the release of excitatory neurotransmitters involved in pain signaling. This combination is particularly effective in conditions such as diabetic neuropathy, postherpetic neuralgia, and peripheral neuropathies, offering symptomatic relief from pain, paresthesia, and numbness. The sustained-release formulation ensures a gradual and consistent release of active ingredients, improving patient compliance and maintaining therapeutic plasma levels over an extended period. Metlin M 75 Tablet SR should be used under medical supervision, with dosage adjustments based on clinical response and tolerability. Common side effects may include dizziness, somnolence, and gastrointestinal disturbances. Caution is advised in patients with renal impairment, and it is contraindicated in individuals with hypersensitivity to either component. This combination therapy provides a synergistic approach to neuropathic pain management, enhancing quality of life for affected patients.