Methosam 200 Tablet contains Ademetionine 200 mg, a naturally occurring compound involved in methylation processes and transsulfuration pathways critical for cellular function. It is primarily indicated for the treatment of liver disorders, including cholestasis, intrahepatic cholestasis of pregnancy, and chronic liver diseases such as cirrhosis and hepatitis. Ademetionine acts as a methyl donor, facilitating the synthesis of phospholipids and glutathione, thereby enhancing hepatocyte membrane stability and promoting detoxification. Additionally, Methosam 200 exhibits anti-inflammatory and antioxidant properties, contributing to the reduction of hepatic injury and improvement of liver function. The tablet is also used as an adjunct in the management of depressive disorders due to its role in neurotransmitter metabolism. Methosam 200 is generally well tolerated; common adverse effects may include gastrointestinal disturbances such as nausea and abdominal discomfort. It is contraindicated in patients with hypersensitivity to Ademetionine or any excipients. Caution is advised in patients with bipolar disorder due to the risk of manic episodes. Dosage and duration of therapy should be individualized based on clinical response and severity of the condition. Methosam 200 Tablet should be used under medical supervision to ensure optimal therapeutic outcomes.