Methico Injection is a parenteral formulation containing Methylcobalamin (1000 mcg), Vitamin B6 (Pyridoxine, 100 mg), and Niacinamide (100 mg), designed to address deficiencies and support neurological and metabolic functions. Methylcobalamin, an active form of Vitamin B12, plays a crucial role in DNA synthesis, nerve regeneration, and hematopoiesis. Vitamin B6 is essential for amino acid metabolism, neurotransmitter synthesis, and immune function, while Niacinamide, a form of Vitamin B3, contributes to cellular energy production and exhibits anti-inflammatory properties. Methico Injection is indicated for the treatment of peripheral neuropathies, vitamin B deficiencies, and conditions requiring enhanced nerve repair and metabolic support. It is particularly beneficial in diabetic neuropathy, alcoholic neuropathy, and other neuropathic disorders where combined B-vitamin therapy accelerates recovery and alleviates symptoms such as paresthesia, numbness, and burning sensations. The injection ensures rapid bioavailability and is administered intramuscularly or intravenously under medical supervision. Methico Injection should be used with caution in patients with hypersensitivity to any component and monitored for potential adverse effects such as allergic reactions or gastrointestinal disturbances. This combination therapy offers a synergistic approach to restoring nerve function and improving patient quality of life in deficiency-related neuropathies.