Memopi HC Cream is a topical formulation containing Hydroquinone 2% w/w, Mometasone 0.1% w/w, and Tretinoin 0.025% w/w, designed for the treatment of hyperpigmentation disorders and inflammatory dermatoses. Hydroquinone acts as a depigmenting agent by inhibiting the enzyme tyrosinase, thereby reducing melanin synthesis and effectively lightening hyperpigmented lesions such as melasma, lentigines, and post-inflammatory hyperpigmentation. Mometasone, a potent corticosteroid, provides anti-inflammatory, antipruritic, and vasoconstrictive effects, helping to reduce erythema, swelling, and irritation associated with inflammatory skin conditions. Tretinoin, a retinoid, promotes epidermal cell turnover and enhances the penetration of hydroquinone, facilitating the removal of pigmented keratinocytes and improving overall skin texture. The combination of these active ingredients offers a synergistic approach to managing resistant hyperpigmentation while controlling inflammation. Memopi HC Cream should be applied once daily to the affected areas as directed by a healthcare professional. Use should be limited to short-term therapy to minimize potential adverse effects such as skin atrophy, irritation, and photosensitivity. Patients are advised to avoid excessive sun exposure and use broad-spectrum sunscreen during treatment to prevent exacerbation of pigmentation. This product is contraindicated in individuals with hypersensitivity to any component and should be used cautiously in pregnancy and lactation.