ME 12 OD Tablet ER is a sustained-release formulation combining Methylcobalamin (1500 mcg), Vitamin B6 (Pyridoxine, 20 mg), and Folic Acid (5 mg), designed to support neurological health and hematopoiesis. Methylcobalamin, an active form of Vitamin B12, plays a crucial role in nerve regeneration, DNA synthesis, and red blood cell formation, making it effective in treating peripheral neuropathies, vitamin B12 deficiency, and related neurological disorders. Vitamin B6 contributes to amino acid metabolism, neurotransmitter synthesis, and immune function, while also aiding in the prevention and management of pyridoxine-responsive neuropathies. Folic Acid is essential for DNA synthesis and repair, and its supplementation helps prevent megaloblastic anemia and supports fetal neural development during pregnancy. The extended-release (ER) formulation ensures gradual absorption, maintaining therapeutic plasma levels and improving patient compliance through once-daily dosing. ME 12 OD Tablet ER is indicated for the treatment of neuropathic pain, vitamin B deficiencies, anemia, and conditions requiring enhanced nerve function and hematological support. It should be used under medical supervision, particularly in patients with known hypersensitivity to B vitamins or those with underlying conditions requiring dose adjustments. Regular monitoring of vitamin levels and clinical response is recommended to optimize therapeutic outcomes.