Mactor F Tablet is a combination medication containing Atorvastatin 10mg and Fenofibrate 160mg, indicated for the management of dyslipidemia and mixed hyperlipidemia. Atorvastatin, a selective HMG-CoA reductase inhibitor, effectively lowers low-density lipoprotein cholesterol (LDL-C) and total cholesterol by inhibiting cholesterol biosynthesis in the liver. Fenofibrate, a fibric acid derivative, primarily reduces triglyceride levels and increases high-density lipoprotein cholesterol (HDL-C) by activating peroxisome proliferator-activated receptor alpha (PPARα), which enhances lipolysis and elimination of triglyceride-rich particles. The combination of these agents provides a comprehensive lipid-lowering effect, targeting multiple lipid fractions to reduce cardiovascular risk in patients with mixed dyslipidemia unresponsive to monotherapy. Mactor F is typically prescribed alongside lifestyle modifications such as diet, exercise, and weight control. It is contraindicated in patients with active liver disease, severe renal impairment, or hypersensitivity to either component. Caution is advised when used concomitantly with other lipid-lowering agents due to the increased risk of myopathy and rhabdomyolysis. Regular monitoring of liver enzymes, renal function, and lipid profile is recommended during therapy to ensure efficacy and safety. Mactor F Tablet should be used under medical supervision with adherence to prescribed dosage.