Mactor 20 Tablet contains Atorvastatin 20 mg, a lipid-lowering agent belonging to the statin class. It is primarily indicated for the management of hypercholesterolemia and mixed dyslipidemia, effectively reducing elevated total cholesterol, low-density lipoprotein cholesterol (LDL-C), and triglycerides while modestly increasing high-density lipoprotein cholesterol (HDL-C). Atorvastatin acts by inhibiting HMG-CoA reductase, the rate-limiting enzyme in cholesterol biosynthesis, thereby decreasing hepatic cholesterol production and upregulating LDL receptors to enhance clearance of LDL from the bloodstream. Mactor 20 is prescribed to reduce the risk of cardiovascular events such as myocardial infarction, stroke, and angina in patients with atherosclerotic cardiovascular disease or those at high risk due to diabetes or multiple risk factors. The tablet is administered orally, typically once daily, with or without food, and dosage adjustments are based on therapeutic response and patient tolerance. Common adverse effects include headache, myalgia, and gastrointestinal disturbances, while serious but rare side effects may involve hepatotoxicity and myopathy. Liver function tests should be monitored periodically. Mactor 20 should be used cautiously in patients with hepatic impairment and contraindicated during pregnancy and lactation. It is essential to combine therapy with lifestyle modifications including diet, exercise, and weight control for optimal lipid management.