Lupitros-Z Eye Drop BKC Free contains Travoprost 0.004% w/v, a prostaglandin analogue indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. Travoprost acts by increasing the outflow of aqueous humor through the uveoscleral pathway, thereby effectively lowering IOP and reducing the risk of optic nerve damage and visual field loss. This formulation is benzalkonium chloride (BKC) free, minimizing the risk of preservative-related ocular surface irritation and making it suitable for patients with sensitive eyes or those requiring long-term therapy. Lupitros-Z Eye Drop is administered once daily, preferably in the evening, to optimize therapeutic efficacy. Common adverse effects may include conjunctival hyperemia, eye irritation, and eyelash changes; however, these are generally mild and transient. Patients should be advised to avoid contact lens use during instillation and to remove lenses prior to application, waiting at least 15 minutes before reinsertion. Caution is recommended in patients with a history of intraocular inflammation or macular edema. Regular monitoring of intraocular pressure and ocular health is essential to assess treatment response and detect potential side effects. Lupitros-Z Eye Drop BKC Free offers an effective and well-tolerated option for managing elevated IOP in glaucoma care.