Lupisulin N 100IU/ml Injection contains Insulin Isophane 100IU, a long-acting insulin formulation used for the management of diabetes mellitus. This intermediate-acting insulin provides basal insulin coverage by mimicking the natural release of insulin from the pancreas, helping to control blood glucose levels over an extended period. Lupisulin N is primarily indicated for patients with type 1 diabetes mellitus who require exogenous insulin for glycemic control, as well as for some patients with type 2 diabetes mellitus when diet, exercise, and oral hypoglycemic agents alone are insufficient. The insulin isophane suspension is typically administered subcutaneously once or twice daily, with dosage individualized based on the patient’s metabolic needs, blood glucose monitoring results, and glycemic control goals. It is important to rotate injection sites to reduce the risk of lipodystrophy. Patients should be educated on recognizing signs of hypoglycemia and hyperglycemia and advised to carry glucose sources for emergency treatment of hypoglycemia. Lupisulin N should not be diluted or mixed with other insulins except as recommended by a healthcare professional. Proper storage conditions must be maintained to preserve insulin potency. Regular monitoring of blood glucose and periodic assessment of HbA1c levels are essential to optimize therapy with Lupisulin N.