Lupin Acp 100mg/325mg Tablet is a combination analgesic and anti-inflammatory medication containing Aceclofenac 100mg and Paracetamol 325mg. Aceclofenac, a non-steroidal anti-inflammatory drug (NSAID), exerts its effect by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), thereby reducing the synthesis of prostaglandins responsible for pain, inflammation, and fever. Paracetamol, an analgesic and antipyretic agent, acts centrally to alleviate pain and reduce fever through inhibition of prostaglandin synthesis in the central nervous system. This combination is indicated for the relief of mild to moderate pain associated with musculoskeletal disorders such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and soft tissue injuries. It is also effective in managing postoperative pain and dental pain. Lupin Acp 100mg/325mg Tablet should be administered as per the physician’s guidance, considering patient-specific factors such as history of gastrointestinal disorders, hepatic or renal impairment, and hypersensitivity to NSAIDs or paracetamol. Caution is advised in patients with cardiovascular risk factors. Common adverse effects include gastrointestinal discomfort, nausea, and dizziness. Regular monitoring and adherence to prescribed dosage are essential to minimize potential risks and ensure therapeutic efficacy.