Lupigest SR 200 Tablet contains 200 mg of natural micronized progesterone, a bioidentical hormone essential for regulating various reproductive functions in the female body. This sustained-release formulation ensures a steady and prolonged release of progesterone, optimizing therapeutic efficacy and maintaining stable plasma levels. Progesterone plays a critical role in the menstrual cycle, supporting the luteal phase and preparing the endometrium for implantation, thereby aiding in the prevention of miscarriage and supporting early pregnancy. It is commonly prescribed for conditions such as luteal phase deficiency, amenorrhea, abnormal uterine bleeding, and as part of hormone replacement therapy in menopausal women. Additionally, it may be used in assisted reproductive technologies to enhance endometrial receptivity. The natural micronized form improves bioavailability and tolerability compared to synthetic progestins. Lupigest SR 200 should be administered under medical supervision, with dosage tailored to individual patient needs based on clinical indication. Contraindications include known hypersensitivity to progesterone, unexplained vaginal bleeding, and certain hormone-sensitive cancers. Common side effects may include dizziness, headache, breast tenderness, and mood changes. Regular monitoring is recommended to assess therapeutic response and detect any adverse effects promptly.