Lucobet GM Cream is a topical formulation combining Clobetasol propionate (0.05% w/w), Miconazole nitrate (2% w/w), and Neomycin sulfate (0.5% w/w), designed for the effective management of inflammatory and infectious dermatoses. Clobetasol, a potent corticosteroid, provides strong anti-inflammatory, antipruritic, and vasoconstrictive effects, thereby reducing redness, swelling, and itching associated with various skin conditions. Miconazole, an imidazole antifungal agent, exhibits broad-spectrum activity against dermatophytes, yeasts, and molds, effectively controlling fungal infections. Neomycin, an aminoglycoside antibiotic, offers antibacterial coverage primarily against gram-negative organisms, preventing or treating secondary bacterial infections that may complicate inflammatory dermatoses. Lucobet GM Cream is indicated for mixed infections where inflammatory skin disorders coexist with fungal and bacterial infections, such as eczema with superimposed candidiasis and bacterial colonization. The cream base ensures adequate skin penetration and local action with minimal systemic absorption. It should be applied as directed by a healthcare professional, typically in a thin layer to the affected area once or twice daily. Use is contraindicated in viral infections, hypersensitivity to any component, and on large areas or broken skin to avoid systemic side effects. Caution is advised during prolonged use due to potential corticosteroid-related adverse effects.