LT-Mac XL Lotion contains Luliconazole 1% w/v, an imidazole antifungal agent effective against a broad spectrum of dermatophytes, yeasts, and molds. It is indicated for the topical treatment of superficial fungal infections such as tinea corporis, tinea cruris, tinea pedis, and pityriasis versicolor. Luliconazole exerts its antifungal action by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes, leading to increased membrane permeability and ultimately fungal cell death. LT-Mac XL Lotion is formulated for once-daily application, promoting patient compliance and convenience. Clinical studies have demonstrated its efficacy and safety profile, with rapid symptomatic relief and mycological cure rates superior to some conventional antifungals. The lotion base facilitates good skin penetration and is well-tolerated with minimal adverse effects, primarily limited to mild local irritation or burning sensation in rare cases. LT-Mac XL Lotion should be applied to the affected area and surrounding skin after cleansing and drying, avoiding contact with eyes and mucous membranes. It is contraindicated in patients with known hypersensitivity to luliconazole or any formulation components. Use during pregnancy and lactation should be under medical supervision. Proper adherence to the prescribed regimen is essential to prevent recurrence and resistance development.