Lozivate-MF Ointment is a topical formulation containing Clobetasol propionate (0.05% w/w), Salicylic Acid (3% w/w), Lactic Acid (3% w/w), and Urea (10% w/w), designed for the management of various dermatological conditions characterized by inflammation, hyperkeratosis, and scaling. Clobetasol propionate, a potent corticosteroid, exerts anti-inflammatory, immunosuppressive, and antiproliferative effects, providing rapid relief from erythema, itching, and swelling. Salicylic Acid acts as a keratolytic agent, facilitating the removal of scales and promoting desquamation, thereby enhancing the penetration of corticosteroids. Lactic Acid, an alpha-hydroxy acid, contributes to skin hydration and mild exfoliation, improving skin texture and barrier function. Urea serves as a humectant and keratolytic, softening hyperkeratotic skin and maintaining moisture balance. Lozivate-MF Ointment is indicated for the treatment of chronic plaque psoriasis, lichen planus, eczema, and other hyperkeratotic dermatoses. It should be applied sparingly to the affected area once or twice daily as directed by a healthcare professional. Caution is advised in prolonged use due to potential corticosteroid-related side effects such as skin atrophy, and it is contraindicated in viral, bacterial, or fungal skin infections. Patient adherence to prescribed duration and monitoring is essential to ensure safety and efficacy.