Lorsaid P 8 Tablet contains a combination of Lornoxicam 8 mg and Paracetamol 325 mg, formulated to provide effective analgesic and anti-inflammatory relief. Lornoxicam, a non-steroidal anti-inflammatory drug (NSAID), exerts its effect by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), thereby reducing the synthesis of prostaglandins responsible for pain, inflammation, and fever. Paracetamol complements this action by providing analgesic and antipyretic effects through central inhibition of prostaglandin synthesis, without significant anti-inflammatory activity. This combination is indicated for the management of moderate to severe pain associated with musculoskeletal disorders, postoperative pain, dental pain, and other inflammatory conditions where both pain relief and reduction of inflammation are desired. Lorsaid P 8 Tablet offers a synergistic effect, enhancing pain control while potentially minimizing the dose-related adverse effects associated with higher doses of individual agents. It should be used with caution in patients with hepatic or renal impairment, gastrointestinal disorders, or a history of hypersensitivity to NSAIDs or paracetamol. Contraindications include active peptic ulcer disease, severe hepatic dysfunction, and known hypersensitivity to any component. Patients are advised to adhere to prescribed dosages and consult healthcare providers if symptoms persist or adverse reactions occur.