Lonitab 10 Tablet contains Minoxidil 10mg, a potent vasodilator primarily indicated for the management of severe hypertension unresponsive to conventional antihypertensive therapies. Minoxidil acts by directly relaxing vascular smooth muscle, leading to peripheral arterial vasodilation and a consequent reduction in systemic vascular resistance and blood pressure. This mechanism facilitates improved blood flow and decreases cardiac workload. Lonitab 10 is typically reserved for patients who require rapid and sustained blood pressure control, often in cases of malignant hypertension or resistant hypertension. Due to its potent vasodilatory effects, Minoxidil may cause reflex tachycardia and sodium and fluid retention; therefore, it is commonly prescribed alongside beta-blockers and diuretics to mitigate these adverse effects. The tablet should be administered orally, with dosage individualized based on patient response and clinical condition, under strict medical supervision. Regular monitoring of blood pressure, heart rate, and renal function is essential during therapy. Lonitab 10 is contraindicated in patients with pheochromocytoma and should be used cautiously in those with ischemic heart disease. Common side effects include hypertrichosis, headache, and edema. Patients are advised to adhere strictly to prescribed doses and report any adverse reactions promptly.