Lithic 400mg Tablet SR contains lithium carbonate, a mood stabilizer primarily used in the management of bipolar disorder. It is indicated for the treatment and prevention of manic and depressive episodes associated with bipolar affective disorder. The sustained-release formulation ensures a gradual release of lithium, maintaining stable plasma concentrations and minimizing peak-related side effects. Lithium carbonate modulates neurotransmitter activity and influences intracellular signaling pathways, contributing to mood stabilization. Dosage must be individualized based on clinical response and serum lithium levels, which require regular monitoring to avoid toxicity. Common adverse effects include gastrointestinal disturbances, tremor, polyuria, and mild cognitive impairment; serious toxicity may manifest as severe neurological symptoms, renal impairment, or cardiac arrhythmias. Patients should maintain adequate hydration and avoid excessive sodium intake to reduce the risk of lithium toxicity. Contraindications include hypersensitivity to lithium, significant renal or cardiovascular disease, and pregnancy unless the benefits outweigh risks. Regular monitoring of renal function, thyroid function, and serum lithium levels is essential during therapy. Lithic 400mg Tablet SR should be used under strict medical supervision to optimize therapeutic outcomes and minimize adverse effects.