Listril 5 Tablet contains Lisinopril 5 mg, an angiotensin-converting enzyme (ACE) inhibitor primarily indicated for the treatment of hypertension and heart failure. By inhibiting the ACE enzyme, Lisinopril reduces the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor, thereby promoting vasodilation and lowering blood pressure. This mechanism helps decrease the workload on the heart and improves cardiac output. Listril 5 is also utilized to improve survival rates following myocardial infarction and to manage diabetic nephropathy by reducing proteinuria and slowing the progression of renal impairment. The tablet is typically administered once daily, with dosage adjustments based on clinical response and patient tolerance. Common adverse effects may include cough, dizziness, hypotension, and hyperkalemia; therefore, monitoring of blood pressure, renal function, and serum electrolytes is recommended during therapy. Listril 5 should be used cautiously in patients with renal artery stenosis, pregnancy, or a history of angioedema related to previous ACE inhibitor therapy. It is contraindicated in the second and third trimesters of pregnancy due to the risk of fetal toxicity. Overall, Listril 5 offers an effective therapeutic option for managing cardiovascular and renal conditions under appropriate medical supervision.