Lipirose-F 10 Tablet

Lipirose-F 10 Tablet
Fenofibrate (145mg) + Rosuvastatin (10mg)
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About This Medicine
Product description & overview
Lipirose-F 10 Tablet contains a combination of Fenofibrate (145 mg) and Rosuvastatin (10 mg), which are lipid-lowering agents used to manage dyslipidemia and reduce cardiovascular risk. Fenofibrate, a fibric acid derivative, primarily decreases triglyceride levels and increases high-density lipoprotein cholesterol (HDL-C) by activating peroxisome proliferator-activated receptor alpha (PPARα), enhancing lipolysis and elimination of triglyceride-rich particles. Rosuvastatin, a potent HMG-CoA reductase inhibitor, reduces low-density lipoprotein cholesterol (LDL-C) by inhibiting cholesterol synthesis in the liver, thereby promoting increased clearance of LDL particles from the bloodstream. The combination therapy is indicated for patients with mixed dyslipidemia, particularly those with elevated triglycerides and LDL-C levels who require comprehensive lipid control. Lipirose-F 10 is also beneficial in reducing the risk of atherosclerotic cardiovascular disease in high-risk individuals. The medication should be used under medical supervision, with periodic monitoring of lipid profiles, liver function tests, and renal parameters to detect potential adverse effects such as hepatotoxicity, myopathy, or rhabdomyolysis. Lifestyle modifications including diet, exercise, and weight management should accompany pharmacotherapy to optimize therapeutic outcomes. Contraindications include active liver disease, severe renal impairment, and hypersensitivity to either component.
Active composition
Fenofibrate 145 mg
+1 more active ingredient
About Fenofibrate
Fenofibrate is a lipid-modifying agent used to treat hyperlipidemia, lowering LDL cholesterol and triglycerides while increasing HDL cholesterol. It works by enhancing lipoprotein lipase activity, promoting fat breakdown. Fenofibrate is effective for managing cholesterol levels. In summary, it is a vital therapy for cardiovascular health.
How It Works
Fenofibrate activates peroxisome proliferator-activated receptor alpha (PPAR-alpha), enhancing lipid metabolism and reducing triglyceride levels.
All Active Ingredients
Rosuvastatin
Rosuvastatin inhibits HMG-CoA reductase, decreasing cholesterol synthesis in the liver and increasing LDL receptor expression.
Dosage & How to Use
Dosage information not available. Please consult your doctor or pharmacist.
Safety Advice
Important precautions
Side Effect Occurrence
Based on clinical trials and patient reports.
Overall Tolerance
Most patients tolerate well
Common Side Effects
Safety Advice
Alcohol
It is unsafe to consume alcohol with Lipirose-F 10 Tablet.
High Risk
Driving
Lipirose-F 10 Tablet does not usually affect your ability to drive.
Exercise Caution
Liver
Lipirose-F 10 Tablet should be used with caution in patients with liver disease. Dose adjustment of Lipirose-F 10 Tablet may be needed. Please consult your doctor. Use of Lipirose-F 10 Tablet is not recommended in patients with severe liver disease and active liver disease.
Regular Checkup
Breastfeeding
Lipirose-F 10 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Consult Doctor
Kidney
Lipirose-F 10 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Lipirose-F 10 Tablet may be needed. Please consult your doctor. Use of Lipirose-F 10 Tablet is not recommended in patients with severe kidney disease.
Regular Checkup
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