Lipirose 5 Tablet contains Rosuvastatin 5 mg, a potent lipid-lowering agent belonging to the statin class. It is primarily indicated for the treatment of hypercholesterolemia and mixed dyslipidemia to reduce elevated total cholesterol, low-density lipoprotein cholesterol (LDL-C), apolipoprotein B, and triglycerides, while increasing high-density lipoprotein cholesterol (HDL-C). Rosuvastatin acts by selectively inhibiting HMG-CoA reductase, the rate-limiting enzyme in cholesterol biosynthesis, leading to decreased cholesterol production and increased clearance of LDL particles from the bloodstream. Lipirose 5 is utilized as an adjunct to diet and lifestyle modifications in patients with primary hyperlipidemia or mixed dyslipidemia, as well as in individuals with homozygous familial hypercholesterolemia. Additionally, it may be prescribed for the prevention of cardiovascular events in patients at high risk due to elevated cholesterol levels. The recommended dose is individualized based on patient response and lipid profile, with regular monitoring of liver function tests and lipid parameters advised during therapy. Common adverse effects include headache, myalgia, and gastrointestinal disturbances, while rare but serious side effects such as myopathy and hepatotoxicity require prompt medical attention. Lipirose 5 should be used cautiously in patients with hepatic impairment and contraindicated during pregnancy and lactation.