Lacfen-SP Tablet is a combination analgesic and anti-inflammatory medication containing Aceclofenac 100 mg, Paracetamol 325 mg, and Serratiopeptidase 15 mg. Aceclofenac, a non-steroidal anti-inflammatory drug (NSAID), provides effective relief from pain and inflammation by inhibiting cyclooxygenase enzymes, thereby reducing prostaglandin synthesis. Paracetamol acts as an analgesic and antipyretic, enhancing pain relief and reducing fever through central inhibition of prostaglandin synthesis. Serratiopeptidase, a proteolytic enzyme, facilitates the breakdown of inflammatory mediators and promotes the resolution of edema and fibrosis, thereby improving tissue healing and reducing swelling. This combination is indicated for the management of acute and chronic musculoskeletal disorders, osteoarthritis, rheumatoid arthritis, postoperative pain, and soft tissue injuries. Lacfen-SP Tablet offers synergistic effects by targeting multiple pathways involved in pain and inflammation, resulting in enhanced efficacy and faster symptom relief. It is generally well-tolerated; however, caution is advised in patients with gastrointestinal ulcers, hepatic or renal impairment, and hypersensitivity to any component. Use under medical supervision is recommended to optimize therapeutic outcomes and minimize adverse effects.