Krose 20 Tablet contains Rosuvastatin 20 mg, a potent lipid-lowering agent belonging to the statin class of medications. It is primarily indicated for the treatment of hypercholesterolemia and mixed dyslipidemia to reduce elevated levels of low-density lipoprotein cholesterol (LDL-C), total cholesterol, and triglycerides, while increasing high-density lipoprotein cholesterol (HDL-C). Rosuvastatin exerts its effect by selectively inhibiting HMG-CoA reductase, the rate-limiting enzyme in cholesterol biosynthesis, thereby decreasing cholesterol production in the liver and promoting increased clearance of LDL particles from the bloodstream. Krose 20 is prescribed for patients at high risk of cardiovascular events, including those with established coronary artery disease, diabetes mellitus, or other risk factors for atherosclerosis. The medication is typically administered once daily, with or without food, and dosage adjustments may be necessary based on therapeutic response and tolerability. Common adverse effects include headache, myalgia, and gastrointestinal disturbances, while rare but serious side effects such as myopathy and hepatotoxicity require regular monitoring of liver function tests and creatine kinase levels. Krose 20 should be used cautiously in patients with pre-existing liver disease or renal impairment and is contraindicated during pregnancy and lactation. Proper adherence to prescribed therapy and lifestyle modifications enhances treatment efficacy and cardiovascular risk reduction.