Kozol Zpto Lotion is a topical formulation containing Ketoconazole 2% w/v and Zinc Pyrithione 1% w/v, indicated for the treatment of various dermatological conditions characterized by fungal and seborrheic manifestations. Ketoconazole, an imidazole antifungal agent, exerts its effect by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes, thereby disrupting fungal growth and replication. Zinc Pyrithione possesses antifungal and antibacterial properties, effectively reducing the proliferation of Malassezia species and other microorganisms implicated in dandruff, seborrheic dermatitis, and related scalp disorders. Kozol Zpto Lotion is primarily utilized for managing seborrheic dermatitis, dandruff, tinea versicolor, and other superficial fungal infections of the skin. The combination of these active ingredients offers a synergistic effect, enhancing therapeutic efficacy and providing symptomatic relief from itching, scaling, and inflammation. The lotion should be applied topically to the affected areas once or twice daily as directed by a healthcare professional. Patients are advised to avoid contact with eyes and mucous membranes. Use during pregnancy or lactation should be under medical supervision. Adverse effects are generally mild and may include local irritation or dryness. Consistent use as prescribed is essential for optimal outcomes.