Korbiliv 450 Tablet SR

Korbiliv 450 Tablet SR
Ursodeoxycholic Acid (450mg)
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About This Medicine
Product description & overview
Korbiliv 450 Tablet SR contains Ursodeoxycholic Acid 450 mg as its active ingredient and is indicated for the treatment of various hepatobiliary disorders. Ursodeoxycholic Acid is a hydrophilic bile acid that exerts cytoprotective, choleretic, and immunomodulatory effects, making it effective in the management of primary biliary cholangitis, cholesterol gallstones, and certain cholestatic liver diseases. Korbiliv 450 Tablet SR facilitates the dissolution of cholesterol-rich gallstones in patients who are not candidates for surgery and improves bile flow by reducing the cholesterol saturation index in bile. Additionally, it protects hepatocytes from bile acid-induced apoptosis and promotes the clearance of toxic bile acids, thereby improving liver function tests and clinical symptoms. The sustained-release formulation ensures a gradual release of the active compound, maintaining therapeutic plasma concentrations over an extended period and enhancing patient compliance. Korbiliv 450 is generally well tolerated, with adverse effects being mild and infrequent, including gastrointestinal disturbances such as diarrhea and abdominal discomfort. It is contraindicated in patients with complete biliary obstruction or hypersensitivity to Ursodeoxycholic Acid. Clinical monitoring and liver function tests are recommended during therapy to assess efficacy and safety.
Active composition
Ursodeoxycholic Acid 450 mg
About Ursodeoxycholic Acid
Ursodeoxycholic acid is a bile acid used primarily in the treatment of gallstones and primary biliary cholangitis, an autoimmune liver disease. It works by reducing cholesterol levels in bile, thus aiding in the dissolution of cholesterol gallstones and improving liver function. Additionally, it is indicated for treating liver diseases in children and is beneficial in managing conditions related to cystic fibrosis. Its clinical significance lies in its ability to enhance bile flow and protect liver cells from damage. In summary, ursodeoxycholic acid is essential for promoting liver health and managing cholesterol-related disorders.
How It Works
Ursodeoxycholic acid reduces cholesterol absorption in the intestine and promotes the dissolution of cholesterol gallstones by decreasing hepatic cholesterol secretion and increasing bile salt concentration.
Dosage & How to Use
Dosage information not available. Please consult your doctor or pharmacist.
Safety Advice
Important precautions
Side Effect Occurrence
Based on clinical trials and patient reports.
Overall Tolerance
Most patients tolerate well
Common Side Effects
Safety Advice
Alcohol
Korbiliv 450 Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Pregnancy
Korbiliv 450 Tablet SR should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Medical Advice
Driving
There is limited information available on the use of Korbiliv 450 Tablet SR in patients with kidney disease. Please consult your doctor.
Exercise Caution
Breastfeeding
Korbiliv 450 Tablet SR does not usually affect your ability to drive.
Consult Doctor
Kidney
Korbiliv 450 Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Korbiliv 450 Tablet SR may be needed. Please consult your doctor.
Regular Checkup
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