Kofegril-DX Syrup is a combination pharmaceutical formulation containing Phenylephrine (5mg/5ml), Chlorpheniramine Maleate (2mg/5ml), and Dextromethorphan Hydrobromide (10mg/5ml). It is indicated for the symptomatic relief of cough and nasal congestion associated with common cold, allergic rhinitis, and upper respiratory tract infections. Phenylephrine acts as a selective alpha-1 adrenergic receptor agonist, providing effective vasoconstriction of nasal mucosa blood vessels, thereby reducing nasal congestion. Chlorpheniramine Maleate is a first-generation antihistamine that competitively inhibits histamine H1 receptors, alleviating allergic symptoms such as sneezing, runny nose, and itching. Dextromethorphan Hydrobromide functions as a centrally acting antitussive agent, suppressing the cough reflex by acting on the medullary cough center without causing significant sedation or respiratory depression. The syrup formulation ensures ease of administration and rapid onset of action. Kofegril-DX Syrup should be used with caution in patients with hypertension, glaucoma, or hyperthyroidism, and is contraindicated in those with known hypersensitivity to any of its components. Dosage adjustments may be necessary in pediatric and elderly populations. Consultation with a healthcare professional is recommended before use to ensure safety and efficacy.