Ketzi Lotion is a topical formulation containing Ketoconazole 2% w/v and Zinc Pyrithione 1% w/v, indicated for the treatment of various fungal and seborrheic skin conditions. Ketoconazole, an imidazole antifungal agent, exerts its effect by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes, thereby disrupting fungal cell growth and replication. Zinc Pyrithione possesses antifungal and antibacterial properties, effectively reducing the proliferation of Malassezia species and other microorganisms implicated in dandruff and seborrheic dermatitis. The combination of these active ingredients provides a broad-spectrum therapeutic effect, making Ketzi Lotion suitable for managing tinea infections, seborrheic dermatitis, and other superficial fungal infections of the skin. Ketzi Lotion is applied topically to the affected area once or twice daily, as directed by a healthcare professional, and should be used consistently for the prescribed duration to achieve optimal results. Common adverse effects may include mild skin irritation, burning sensation, or dryness at the application site. Patients are advised to avoid contact with eyes and mucous membranes and to discontinue use if hypersensitivity reactions occur. Ketzi Lotion offers an effective and well-tolerated option for managing fungal skin infections and associated inflammatory conditions.