Ketorol Gel contains Ketorolac 20mg, a nonsteroidal anti-inflammatory drug (NSAID) indicated for the topical treatment of pain and inflammation associated with musculoskeletal conditions such as sprains, strains, and contusions. Ketorolac exerts its effect by inhibiting cyclooxygenase (COX-1 and COX-2) enzymes, thereby reducing the synthesis of prostaglandins, which are mediators of inflammation and pain. The gel formulation allows for localized delivery, minimizing systemic exposure and reducing the risk of systemic side effects commonly associated with oral NSAIDs. Ketorol Gel is applied directly to the affected area, providing targeted relief of acute pain and inflammation. It is suitable for short-term use and should be applied in a thin layer, avoiding broken or irritated skin. Common adverse reactions may include mild local irritation, redness, or itching at the application site. Ketorol Gel is contraindicated in patients with known hypersensitivity to ketorolac, other NSAIDs, or any component of the formulation. Caution is advised in patients with a history of gastrointestinal ulceration or bleeding, renal impairment, or cardiovascular disease. Use during pregnancy and lactation should be avoided unless clearly necessary and under medical supervision. Ketorol Gel offers an effective topical option for managing localized inflammatory pain with a favorable safety profile when used as directed.