Ketoprime Lotion contains Ketoconazole 2% w/v, an imidazole antifungal agent effective in the treatment of various superficial fungal infections of the skin. Ketoconazole exerts its antifungal activity by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes, leading to increased membrane permeability and ultimately fungal cell death. This lotion is indicated for the management of dermatophytosis, pityriasis versicolor, seborrheic dermatitis, and candidiasis affecting the skin. Ketoprime Lotion is applied topically to the affected area once or twice daily, depending on the severity and type of infection, and should be used for the full prescribed duration to prevent recurrence. It is generally well tolerated, with adverse effects being rare but may include local irritation, itching, or redness at the application site. Patients should avoid contact with eyes and mucous membranes, and the lotion should not be applied to broken or inflamed skin unless directed by a healthcare professional. Ketoprime Lotion is contraindicated in individuals with known hypersensitivity to ketoconazole or any of the formulation components. Use during pregnancy and lactation should be under medical supervision. Proper hygiene and adherence to treatment regimens enhance therapeutic outcomes and reduce the risk of reinfection.